検索結果

Search Results for " tumor metastasis "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T10425	AZ084		CCR
	AZ084 is a potent, selective, allosteric, and oral active CCR8 antagonist (Ki: 0.9 nM). It has the potential to treat asthma.		CCR
T8310	MMP-9-IN-1		MMP
	MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).		MMP
T5465	PF-5274857	PF-5274857 freebase	Smo
	PF-5274857 (PF-5274857 free base) is an effective and selective hedgehog signaling pathway inhibitor (IC50: 5.8 nM and a Ki: 4.6 nM). PF-5274857 is a potentially attractive clinical candidate for the treatment of tumor t...		Smo
T36758	CAIX Inhibitor S4	S4	Carbonic Anhydrase
	CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively. The Kis for CA II and CA I are 546 and 5600 nM.		Carbonic Anhydrase
T9963	MPT0B390		HDAC
	MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.		HDAC
T24642	YH-306	YH306,TRV055 acetate (25849-90-5 Free base)	MMP , MMP , FAK , Rho , PI3K , Src
	YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.		MMP , MMP , FAK , Rho , PI3K , Src
T15574	Incyclinide	COL-3,CMT-3	MMP
	Incyclinide (COL-3) is a matrix metalloproteinase (MMP) inhibitor. Thereby causing extracellular matrix degradation, tumor growth and invasion, and inhibiting angiogenesis, and metastasis.		MMP
T28212	NSC668394	NSC-668394,NSC 668394	PKC
	NSC668394 is a potent small molecule ezrin (Thr567) phosphorylation inhibitor.NSC668394 has potential antitumor activity by inhibiting ezrin T567 phosphorylation and increasing Ca2+-dependent ezrin cleavage.NSC668394 can...		PKC
T6011	Batimastat	BB94	MMP
	Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.		MMP
T9107	NP-G2-044		Others
	NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.		Others
T27613	InS3-54-A26		STAT
	inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.		STAT
T14496	BAMB-4	ITPKA-IN-C14	Others
	BAMB-4 (ITPKA-IN-C14) is a highly membrane-permeable inhibitor of inositol-1,4,5-trisphosphate-3-kinase A (ITPKA). It acts by suppressing the metastasis-promoting effect of ITPKA in lung tumor cells(with IC50 of 37 μM in...		Others
TP1472	Tyroserleutide		Others
	Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of h...		Others
T77059	Leronlimab	PRO 140	CCR
	Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. leronlimumab has both anti-HIV and anti-tumor activity, inhibiting CCR-mediated HIV-1 virus and cancer cell metastasis in mouse tumor models. Leronl...		CCR
T26629	Angstrom6	A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide	PAI-1
	Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...		PAI-1
T9398	NSC 73150	NSC 97967	Others
	6-methyl-2-[2-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]hydraziny l]-1H-pyrimidin-4-one (NSC 73150) is a pyrimidine derivative with antitumor activity. Preclinical studies have shown that it inhibits the growth of a...		Others
TP1526L1	Fibronectin CS1 Peptide acetate		Others
	CS1 peptide is present within type III homology connecting segment (IIICS) as well as C-274 (cell-binding domain). Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in sp...		Others
T29231	ZLD1039	ZLD-1039,ZLD 1039	Histone Methyltransferase
	ZLD1039 is a potent, orally bioavailable EZH2 (Enhancer of Zeste Homolog 2) inhibitor with high selectivity. It demonstrates strong, concentration-dependent inhibition of both wild-type and mutant (Y641F and A677G) PRC2 ...		Histone Methyltransferase
TP1345	Kisspeptin-10, human (TFA)(374675-21-5,FREE)		GPR , Kisspeptin
	Kisspeptin-10, human TFA is a potent vasoconstrictor and angiogenesis inhibitor. Kisspeptin-10, human TFA acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role i...		GPR , Kisspeptin
T77743	TT-012		Others
	TT-012 has anti-tumor activity, selectively binds dynamic MITF and disrupts the dimer formation and DNA binding of the latter. TT-012 can inhibit the transcription of MITF in B16F10 melanoma cells. TT-012 inhibited the g...		Others
T25765	LY52	LY-52,LY 52
	LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.
T69503	ABT-518
	ABT-518 is an inhibitor of matrix metalloproteinases, which are associated with tumor growth and development of metastasis.
T13961	Vitamin CK3		Others
	Vitamin CK3 is the combination of Vitamin C and vitamin K3 and has been shown to inhibit tumor growth and lung metastasis.		Others
T24954	YF479	YF-479,YF 479
	YF479 is an inhibitor of histone deacetylase that acts by inhibiting breast tumor growth, metastasis, and recurrence.
T71351	STAT3-IN-A69
	STAT3-IN-A69 is an inhibitor targeting the DNA-binding domain of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo.
T70051	MMI-166
	MMI-166 is a selective matrix metalloproteinase (MMP) inhibitor that prevents tumor invasion and metastasis by downregulating the activity of MMP-2 and MMP-9.
T28478	PZ-285	PZ 285
	PZ-285 is a potent anticancer agent with similar antitumor activity to the clinically active agent Dox. Pz 285 improves survival, inhibits primary tumor regrowth, and inhibits lung tumor metastasis compared to vehicle co...
T10273	AhR modulator-1		Others
	AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrog...		Others
T70052	S-3304
	S-3304 is a n orally-agent agent with potential antineoplastic activity. S-3304 inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and ...
T61118	CD73-IN-12
	CD73-IN-12 is a highly effective CD73 inhibitor that displays strong potential in tumor suppression. CD73, an enzyme intricately linked to tumor development, angiogenesis, and metastasis, is significantly inhibited by CD...
T61090	CD73-IN-8
	CD73-IN-8, a potent CD73 inhibitor, prevents the catalytic activity of CD73, an enzyme responsible for converting extracellular 5'-phosphate adenosine (5'-AMP) to adenosine. Adenosine, once produced, can induce immunosup...
T35495	(±)13(14)-DiHDPA
	(±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. Epoxygenase metabolites of DHA, including (±)13(14)-DiHDPA, are reported to inhibit angiogenesis, t...
T80992	Thrombospondin (TSP-1)-derived CD36 binding motif
	Thrombospondin-1 (TSP-1)-derived CD36 binding motif is a bioactive peptide cyclized by a disulfide bond, critical for TSP-1-CD36 interaction. Involved in cancer metastasis, tumor adhesion, and angiogenesis, this matrix-b...
T69028	CJ-463
	CJ-463 is a potent ans selective uPA inhibitor. Treatment with CJ-463 resulted in a significant inhibition of primary tumor growth, with the highest efficacy seen in the 100 mg/kg group. Urokinase (uPA) plays a crucial r...
T81708	Nagrestipen
	Nagrestipen, a variant of the human macrophage inflammatory protein-1 alpha (MIP-1α), also referred to as ECI 301, exhibits antitumor activity. It is employed in therapeutic trials focused on cancer, assessing its effica...
TP1526	Fibronectin CS1 Peptide
	he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively i...
T78826	LN5P45
	LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1].
T71187	Foretinib phosphate
	Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vas...
T82645	Cyclic PSAP peptide
	Cyclic PSAP peptide (DWLPK) possesses properties akin to those of a therapeutic agent, demonstrating the potential to inhibit metastasis and suppress tumor growth in vivo [1].
T60779	CD73-IN-13
	CD73-IN-13 is able to be used in a medicament preparing for tumor-related diseases. CD73-IN-13 is a potent inhibitor of CD73 which is closely associated with tumor growth, angiogenesis and metastasis [1].
T70344	BJ-2302
	BJ-2302 is a SRC inhibitor. BJ-2302 effectively suppressed MDA-MB-231 cell invasion (Matrigel invasion assay) and metastasis (chorioallantoic membrane assay xenografted with MDA-MB-231-luc2-tdTomato cancer cells). Additi...
T79284	IR-251
	IR-251 is a mitochondrion-targeting near-infrared (NIR) fluorescent probe that selectively accumulates in tumor cell mitochondria through organic anion transporting polypeptides (OATPs), leading to mitochondrial dysfunct...
T75154	ATU027
	ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, ...
T61000	CD73-IN-10
	CD73-IN-10 can be used in preparing tumor-related diseases medicament. CD73-IN-10 is a potent CD73 inhibitor that can catalyze the adenosine production from extracellular 5'-phosphate adenosine (5'-AMP). Adenosine induce...
T60599	CD73-IN-7
	CD73-IN-7 is a potent CD73 inhibitor that can be used for preparing a medicament for tumor-related diseases. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP) which can indu...
T60844	CD73-IN-9
	CD73-IN-9 is a potent CD73 inhibitor that be used in preparing the tumor-related diseases medicament. CD73 can catalyze the adenosine production from extracellular 5'-phosphate adenosine (5'-AMP). The adenosine can induc...
T79410	Anti-TNBC agent-3
	Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties. It effectively inhibits tumor growth and metastasis in xenograft models of triple-negative bre...
T35587	Ganglioside GD1a mixture (sodium salt)	Ganglioside B1
	Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it i...
T80127	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro		Integrin
	FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties. This compound impedes tumor cell adherence to endothelial blood vessel cells, potentially ...		Integrin
T61053	CD73-IN-11
	CD73-IN-11 is able to used for tumor-related diseases medicament preparing. CD73-IN-11 is an effective CD73 inhibitor. CD73 can catalyze the production of adenosine from extracellular 5'-phosphate adenosine (5'-AMP) whic...

Compounds

Synonym: PF-5274857 freebase

Target: Carbonic Anhydrase

Synonym: YH306,TRV055 acetate (25849-90-5 Free base)

Target: MMP, MMP, FAK, Rho, PI3K, Src

Synonym: NSC-668394,NSC 668394

Synonym: ITPKA-IN-C14

Synonym: A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide

Fibronectin CS1 Peptide acetate

Synonym: ZLD-1039,ZLD 1039

Target: Histone Methyltransferase

Kisspeptin-10, human (TFA)(374675-21-5,FREE)

TP1345

Synonym:

Target: GPR, Kisspeptin

Synonym: YF-479,YF 479

Thrombospondin (TSP-1)-derived CD36 binding motif

Fibronectin CS1 Peptide

Ganglioside GD1a mixture (sodium salt)

T35587

Synonym: Ganglioside B1

Target:

FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro

カタログ番号	製品名	別名	ターゲット
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T2982	Xanthone	Genicide,Xanthenone,Benzophenone oxide	Apoptosis , Others , Influenza Virus , Antibacterial , Antifungal
	Xanthone (Xanthenone) is currently used as ovicide for codling moth eggs and as a larvicide.
T8169	Decursinol		Others
	Decursinol is isolated from the roots of Angelica Gigas with an antinociceptive effect. It also has anti-tumor and anti-metastasis activity.		Others
T3402	20(S)-Ginsenoside Rg3	20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
	20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
T75643	Isoxanthohumol		HSV
	Isoxanthohumol is a prenylated flavonoid derived from hops and beer with antiproliferative activity against several human cancer cell lines.Isoxanthohumol inhibits the metastasis or invasion of lung metastases of tumor c...		HSV
T3229	Cytochalasin D		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
	Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertilization processes such as sperm penetration or sperm head dec...		ATPase , p38 MAPK , Calcium Channel , Akt , PI3K
T23773	Barbigerone	Barubigeron
	Barbigerone is a tumor angiogenesis, growth, and metastasis inhibitor in melanoma.
TN4166	Griffipavixanthone		ERK , Raf , ROS , MEK , Caspase
	Griffipavixanthone inhibits the growth of human Non-small-cell lung cancer H520 cells in dose- and time-dependent manners, it induces cell apoptosis through mitochondrial apoptotic pathway accompanying with ROS productio...		ERK , Raf , ROS , MEK , Caspase
TN3587	Capillarisin		MMP , ERK , IL Receptor , BCL , VEGFR , TNF , NOS , NF-κB , TLR , MAPK , COX , DNA/RNA Synthesis , Prostaglandin Receptor , JNK , STAT
	Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by ...
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs =...

天然物製品

Gefitinib

T1181

Synonym: ZD1839

Target: EGFR, Tyrosine Kinases, Autophagy

Xanthone

T2982

Synonym: Genicide,Xanthenone,Benzophenone oxide

Target: Apoptosis, Others, Influenza Virus, Antibacterial, Antifungal

20(S)-Ginsenoside Rg3

T3402

Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Target: ATPase, p38 MAPK, Calcium Channel, Akt, PI3K

Target: ERK, Raf, ROS, MEK, Caspase

Capillarisin

TN3587

Synonym:

Target: MMP, ERK, IL Receptor, BCL, VEGFR, TNF, NOS, NF-κB, TLR, MAPK, COX, DNA/RNA Synthesis, Prostaglandin Receptor, JNK, STAT

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00305	TGFBR1 Protein, Human, Recombinant (mFc & Avi)	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-02030	CD82 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras...
TMPY-00476	ITGB1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involv...
TMPY-00566	CCL18 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its...
TMPK-00293	Nectin-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymp...
TMPK-00260	CD155/PVR Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells...
TMPH-01060	Cathepsin F Protein, Human, Recombinant (His)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis. Cathepsin F Protein, Human, Recombinant (His) is expressed...
TMPY-04467	NME1 Protein, Human, Recombinant (His)	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the inter...
TMPH-01059	Cathepsin B Protein, Human, Recombinant (GST)	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobuli...
TMPK-01256	CDCP1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-00635	CDCP1 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-00339	ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00341	ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-00340	ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression pr...
TMPK-01182	CDCP1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01255	CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated	Cynomolgus	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01181	CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01010	CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-01183	CDCP1 Protein, Human, Recombinant (aa 30-368, His)	Human	HEK293 Cells
	Tumor metastasis depends on the dynamic regulation of cell adhesion through β1-integrin. The Cub-Domain Containing Protein-1, CDCP1, is a transmembrane glycoprotein which regulates cell adhesion. Overexpression and loss ...
TMPK-00306	TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated	Human	HEK293 Cells
	transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPK-00899	EPHA5 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may th...
TMPK-00529	EPHA5 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 5 (EphA5) expression was detected in all non-tumor gastric epithelia but was differentially expressed among gastric cancer samples. EphA5 is differentially expressed in gastric cancer. EphA5 may th...
TMPK-00172	B7-H4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A solu...
TMPJ-00159	EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermato...
TMPJ-01113	RCN2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Reticulocalbin-2 (RCN2, also named as ERC-55), is a 55-kDa Ca2+-binding protein containing six EF-hands, which was identified to be localized in endoplasmic reticulum. RCN2 is belonging to Reticulocalbin (RCN) family, th...
TMPY-04084	ANGPTL1 Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Angiopoietin-like protein 1 (ANGPTL1) has been reported to suppress migration and invasion in lung and breast cancer, acting as a novel tumor suppressor candidate. Downregulation of tumor suppressor signaling plays an im...
TMPK-00051	IL-20 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-00052	IL-20 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-01198	IL-20 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPY-00886	MMP-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the ma...
TMPK-01197	IL-20 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPY-05075	PDGFA Protein, Canine, Recombinant (His)	Canine	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-05068	PDGFA Protein, Rat, Recombinant (His)	Rat	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle,...
TMPJ-00447	MMP-3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue rem...
TMPY-05250	CLEC3A Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicate...
TMPJ-00508	CTSL Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tu...
TMPJ-00203	Galectin-9 Protein, Human, Recombinant (GST)	Human	E. coli
	Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forss...
TMPY-04838	PDGFA Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-00455	PDGFA Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPY-05056	PDGFA Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell prolifera...
TMPJ-01137	MIA Protein, Human, Recombinant (His)	Human	E. coli
	Melanoma Inhibitory Activity Protein (MIA) is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells, which was the first discovered member of a family of secreted cytokines termed...
TMPJ-01432	CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated	Human	HEK293 Cells
	MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by t...
TMPH-02697	GNA12 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF12/LARG). G...
TMPJ-01433	Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated	Human	E. coli
	Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components ...
TMPJ-00578	CEACAM21 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carcinoembryonic antigen-related cell adhesion molecule 21 is a protein that in humans is encoded by the CEACAM21 gene. It belongs to the immunoglobulin superfamily. CEA family.containing 1 Ig-like C2-type (immunoglobuli...
TMPY-01576	Artemin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
TMPY-03397	TPPP3 Protein, Human, Recombinant (His)	Human	E. coli
	TPPP3, a member of the Tubulin polymerization-promoting protein family, is an intrinsically unstructured protein that induces tubulin polymerization. TPPP3 is a marker in the developing musculoskeletal system. In tendons...
TMPJ-00022	LGALS7 Protein, Human, Recombinant	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also poss...
TMPY-04417	DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)	Human	Baculovirus Insect Cells
	Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK...
------------------------ More ------------------------

TGFBR1 Protein, Human, Recombinant (mFc & Avi)

TMPK-00305

Species: Human

Expression System: HEK293 Cells

CD82 Protein, Human, Recombinant (His)

TMPY-02030

Species: Human

Expression System: HEK293 Cells

ITGB1 Protein, Human, Recombinant (His)

TMPY-00476

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

Nectin-2 Protein, Human, Recombinant (His & Avi)

TMPK-00293

Species: Human

Expression System: HEK293 Cells

CD155/PVR Protein, Human, Recombinant (His & Avi)

TMPK-00260

Species: Human

Expression System: HEK293 Cells

Cathepsin F Protein, Human, Recombinant (His)

TMPH-01060

Species: Human

Expression System: E. coli

NME1 Protein, Human, Recombinant (His)

TMPY-04467

Species: Human

Expression System: E. coli

Cathepsin B Protein, Human, Recombinant (GST)

TMPH-01059

Species: Human

Expression System: E. coli

CDCP1 Protein, Cynomolgus, Recombinant (His)

TMPK-01256

Species: Cynomolgus

Expression System: HEK293 Cells

CDCP1 Protein, Rat, Recombinant (His)

TMPK-00635

Species: Rat

Expression System: HEK293 Cells

ALCAM Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-00339

Species: Mouse

Expression System: HEK293 Cells

ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00341

Species: Human

Expression System: HEK293 Cells

ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00340

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (hFc)

TMPK-01182

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

TMPK-01255

Species: Cynomolgus

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-01181

Species: Human

Expression System: HEK293 Cells

CDCP1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-01010

Species: Mouse

Expression System: HEK293 Cells

CDCP1 Protein, Human, Recombinant (aa 30-368, His)

TMPK-01183

Species: Human

Expression System: HEK293 Cells

TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated

TMPK-00306

Species: Human

Expression System: HEK293 Cells

EPHA5 Protein, Human, Recombinant (His)

TMPK-00899

Species: Human

Expression System: HEK293 Cells

EPHA5 Protein, Cynomolgus, Recombinant (His)

TMPK-00529

Species: Cynomolgus

Expression System: HEK293 Cells

B7-H4 Protein, Human, Recombinant (His & Avi)

TMPK-00172

Species: Human

Expression System: HEK293 Cells

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00159

Species: Human

Expression System: HEK293 Cells

RCN2 Protein, Human, Recombinant (His)

TMPJ-01113

Species: Human

Expression System: HEK293 Cells

ANGPTL1 Protein, Canine, Recombinant (hFc)

TMPY-04084

Species: Canine

Expression System: HEK293 Cells

IL-20 Protein, Human, Recombinant (hFc)

TMPK-00051

Species: Human

Expression System: HEK293 Cells

IL-20 Protein, Human, Recombinant (His)

TMPK-00052

Species: Human

Expression System: HEK293 Cells

IL-20 Protein, Mouse, Recombinant (His)

TMPK-01198

Species: Mouse

Expression System: HEK293 Cells

MMP-1 Protein, Human, Recombinant (His)

TMPY-00886

Species: Human

Expression System: HEK293 Cells

IL-20 Protein, Mouse, Recombinant (hFc)

TMPK-01197

Species: Mouse

Expression System: HEK293 Cells

PDGFA Protein, Canine, Recombinant (His)

TMPY-05075

Species: Canine

Expression System: P. pastoris (Yeast)

PDGFA Protein, Rat, Recombinant (His)

TMPY-05068

Species: Rat

Expression System: P. pastoris (Yeast)

EFNA3 Protein, Mouse, Recombinant (hFc)

TMPJ-00114

Species: Mouse

Expression System: HEK293 Cells

MMP-3 Protein, Human, Recombinant (His)

TMPJ-00447

Species: Human

Expression System: HEK293 Cells

CLEC3A Protein, Mouse, Recombinant (His)

TMPY-05250

Species: Mouse

Expression System: Baculovirus Insect Cells

CTSL Protein, Human, Recombinant (His)

TMPJ-00508

Species: Human

Expression System: HEK293 Cells

Galectin-9 Protein, Human, Recombinant (GST)

TMPJ-00203

Species: Human

Expression System: E. coli

PDGFA Protein, Mouse, Recombinant (His)

TMPY-04838

Species: Mouse

Expression System: P. pastoris (Yeast)

PDGFA Protein, Canine, Recombinant (hFc)

TMPY-00455

Species: Canine

Expression System: HEK293 Cells

PDGFA Protein, Human, Recombinant (His)

TMPY-05056

Species: Human

Expression System: P. pastoris (Yeast)

MIA Protein, Human, Recombinant (His)

TMPJ-01137

Species: Human

Expression System: E. coli

CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

TMPJ-01432

Species: Human

Expression System: HEK293 Cells

GNA12 Protein, Mouse, Recombinant (His & Myc)

TMPH-02697

Species: Mouse

Expression System: E. coli

Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated

TMPJ-01433

Species: Human

Expression System: E. coli

CEACAM21 Protein, Human, Recombinant (His)

TMPJ-00578

Species: Human

Expression System: HEK293 Cells

Artemin Protein, Mouse, Recombinant (hFc)

TMPY-01576

Species: Mouse

Expression System: HEK293 Cells

TPPP3 Protein, Human, Recombinant (His)

TMPY-03397

Species: Human

Expression System: E. coli

LGALS7 Protein, Human, Recombinant

TMPJ-00022

Species: Human

Expression System: E. coli

DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

TMPY-04417

Species: Human

Expression System: Baculovirus Insect Cells

--------- More ---------

カタログ番号	製品名
L2100	Anti-Cancer Compound Library	7234 compounds
	A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L2200	Tyrosine Kinase Inhibitor Library	1016 compounds
	A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases;
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L7600	Chemokine Inhibitor Library	59 compounds
	A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；

ライブラリー

Anti-Cancer Compound Library

L2100

Compounds: 7234

Tyrosine Kinase Inhibitor Library

L2200

Compounds: 1016

Angiogenesis related Compound Library

L4800

Compounds: 1353

Chemokine Inhibitor Library

L7600

Compounds: 59

HIF-1 Signaling Pathway Compound Library

L8500

Compounds: 1336